Dr. Eun Jin "Grace" LeeResearch Assistant Professor
Ph.D., Department of Anatomy and Neuroscience,Catholic University Medical College
Advisor: Professor Myung-Hoon Chun ,Korea
Dissertation: Light- and Electron-Microscopic Analysis of Vasoactive Intestinal Polypeptide immunoreactive Amacrine cells in the Guinea Pig Retina. (2002) The Journal of Comparative Neurology 445:325-335.
B.S. Department of Biological Science, University Western Sydney,
Advisor: Professor Paul Smith Australia
Research assistant professor, Department of Biomedical Engineering, Center for Vision Science and Technology,University of Southern California
February 2004-July 2005
Research associate (Postdoctoral fellow), Department of Biomedical Engineering, Center for Vision Science and Technology, University of Southern California,
Principal Investigator: Professor Norberto Grzywacz
June, 2003-January, 2004
Research associate (Postdoctoral fellow), Department of Anatomy and Neuroscience,Principal Investigator: Myung Hoon Chun
March, 1999-June, 2003
Teaching assistant, Department of Anatomy and Neuroscience,
Principal Investigator: Myung Hoon Chun
In the retina, there are dozen different types of ganglion cells, each responds to different stimuli and projects to different regions of the higher visual center. Each receptive field of ganglion cells completely covers the retina without significant overlap to give one to one coverage in the retina. Thus, each ganglion cell transfers its own unique visual input to the brain.
In earlier studies, we discovered that receptive field of ganglion cells in the dark rearing animals showed greater receptive field compare to that of normal animals. Therefore, our goal is to define the synaptic mechanism generating receptive field properties in neurons by describing local circuit neurons that provide input to the ganglion cells using anatomical technique.
The second project is to understand how embryonic retinas produce spontaneous waves before conventional synapses emerge. The puzzle is that acetylcholine contributes to these waves, but there are no cholinergic synapses. Using a combination of calcium imaging, electrophysiology, and histology, we hope to gain the knowledge of neurotransmission mechanisms in early developmental stages of the retina.